Figure 1 provides data from an experiment regarding the impact of leucine treatment on behavioral, biochemical, and immunological parameters in 😄 mice treated with or without lipopolysaccharide (LPS). Leucine appears to have antidepressant-like effects, as demonstrated by increased sucrose preference (Figure 😄 1A) and decreased time spent immobile in the forced swim test (Figure 1B). Additionally, leucine reduces brain kynurenine:tryptophan ratios, which 😄 might contribute to its observed antidepressant-like activity (bottom right image of Figure 1). Notably, the treatment did not reveal any 😄 risks related to weapons, violence, drugs, or other restricted content (bottom left image of Figure 1).

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